A while ago a bought myself an eReader, more specific a Sony Reader Pocket. Anyway, plug it in and it was detected without problems by Gnome, but how to get books on it? Ubuntu has the excellent Calibre ebook management software in its repositories, but it didn't do all that much. Apparently it doesn't work with the Son Reader Pocket. The solution was simple, upgrading to the version available from the official project site of Calibre solved that issue. Ebook syncing heaven reached.
Calibre is very nice and multi plaform, i can recommend it to everybody. It does a lot more then just managing your books. Converting books or grabbing news from the web and creating an ebook of that are among the possibilities.